Cleaved-Cathepsin D HC (L169) Polyclonal Antibody

CTSD encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in CTSD play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.

The Cleaved-Cathepsin D HC (L169) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and quantification of cleaved cathepsin D in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target protein.

Cathepsin D is a lysosomal aspartic protease that plays a crucial role in the degradation of intracellular proteins. Cleaved cathepsin D is an active form of the enzyme, which is generated by proteolytic processing. It has been implicated in various physiological and pathological processes, including cancer progression, neurodegenerative diseases, and tissue remodeling.

The Cleaved-Cathepsin D HC (L169) Polyclonal Antibody has been extensively validated for its performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) applications. It exhibits exceptional sensitivity and specificity, enabling accurate and reproducible detection of cleaved cathepsin D in complex biological samples.

This antibody is supplied as a purified and concentrated solution, ensuring optimal performance and ease of use. It is compatible with a wide range of sample types, including tissue sections, cell lysates, and biological fluids. The Cleaved-Cathepsin D HC (L169) Polyclonal Antibody is suitable for both research and diagnostic purposes, facilitating the investigation of cathepsin D-mediated processes in various biological contexts.

In summary, the Cleaved-Cathepsin D HC (L169) Polyclonal Antibody is a highly reliable and specific tool for the detection and quantification of cleaved cathepsin D. Its exceptional performance in various applications makes it an invaluable asset for researchers and clinicians studying the role of cathepsin D in health and disease.