Cleaved-KLK8 (V33) Polyclonal Antibody

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK8 is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. Kallikrein related peptidase 8 may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of KLK8 results in multiple transcript variants encoding different isoforms.

The Cleaved-KLK8 (V33) Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of cleaved-KLK8 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the cleaved-KLK8 protein sequence. The resulting polyclonal antibody exhibits high affinity and specificity towards the cleaved-KLK8 protein, making it an ideal tool for research applications.

The Cleaved-KLK8 (V33) Polyclonal Antibody is suitable for use in a variety of immunoassays, including Western blotting, immunohistochemistry, and ELISA. It has been validated for use in human, mouse, and rat samples, and has been shown to exhibit minimal cross-reactivity with other related proteins. This antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

In summary, the Cleaved-KLK8 (V33) Polyclonal Antibody is a reliable and effective tool for the detection and quantification of cleaved-KLK8 protein in various biological samples. Its high specificity and sensitivity make it an ideal choice for researchers studying the role of cleaved-KLK8 in various physiological and pathological processes.