CNPase Polyclonal Antibody

2',3'-cyclic nucleotide-3'-phosphodiesterase (CNPase) is a membrane-bound enzyme that can link tubulin to membranes and may regulate cytoplasmic microtubule distribution. CNPase acts as a microtubule-associated protein by promoting microtubule assembly; this activity resides in the C-terminus of the enzyme. CNPase is firmly associated with tubulin from brain tissue and thyroid cells and can be found at high concentrations in central nervous system myelin and in the outer segments of photoreceptors in the retina. Acute lead intoxication leads to disturbances in CNPase activity and the morphology of myelin.

The CNPase Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of CNPase protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of CNPase protein. The CNPase Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

This antibody is suitable for use in both research and diagnostic applications. The CNPase Polyclonal Antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. This antibody is available in various sizes to meet the needs of different applications. With its high specificity and sensitivity, the CNPase Polyclonal Antibody is an essential tool for researchers and clinicians studying the role of CNPase protein in various biological processes.

The CNPase Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of CNPase protein in various biological samples. This antibody has been meticulously developed using advanced techniques to ensure exceptional performance and reliability.

CNPase, also known as 2',3'-cyclic nucleotide 3'-phosphodiesterase, is a key enzyme involved in the myelination process of the central nervous system. It plays a crucial role in the formation and maintenance of myelin sheaths, which are essential for the proper functioning of neurons. Dysregulation of CNPase expression has been implicated in various neurological disorders, making it an important target for research and diagnostic purposes.

The CNPase Polyclonal Antibody exhibits high affinity and specificity towards CNPase protein, enabling accurate detection and quantification in a wide range of sample types, including tissue lysates, cell extracts, and biological fluids. It has been rigorously validated for use in various applications, such as Western blotting, immunohistochemistry, and immunofluorescence.

This antibody offers numerous advantages, including its exceptional sensitivity, low background noise, and robust performance across different experimental conditions. It has been extensively tested to ensure minimal cross-reactivity with other proteins, ensuring reliable and accurate results. Additionally, it exhibits excellent reproducibility, allowing for consistent and precise measurements.

The CNPase Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy customization and optimization of experimental protocols. Each batch of antibody undergoes stringent quality control procedures to guarantee batch-to-batch consistency and reliability.

In summary, the CNPase Polyclonal Antibody is a highly reliable and specific tool for the detection and quantification of CNPase protein. Its exceptional performance, sensitivity, and versatility make it an invaluable asset for researchers and clinicians studying the role of CNPase in neurological disorders and myelination processes.