This gene encodes the alpha chain of type XII collagen, a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen family. Type XII collagen is a homotrimer found in association with type I collagen, an association that is thought to modify the interactions between collagen I fibrils and the surrounding matrix. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
Immunofluorescence analysis of COS7 cells, using Collagen XII alpha1 Antibody. The picture on the right is blocked with the synthesized peptide.
Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using Collagen XII alpha1 Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of the lysates from HeLa cells using ADD2 antibody.