Daxx(Phospho Ser668) Polyclonal Antibody

This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins| such as apoptosis antigen Fas| centromere protein C| and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus| the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm| the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications| including sumoylation| phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript varian

The Daxx(Phospho Ser668) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Daxx protein phosphorylated at Ser668. This antibody has been meticulously developed using advanced techniques to ensure exceptional performance and reliability in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The Daxx(Phospho Ser668) Polyclonal Antibody exhibits outstanding specificity, exhibiting minimal cross-reactivity with non-phosphorylated Daxx protein or other related proteins. This high specificity allows for accurate and precise analysis of Daxx phosphorylation status, enabling researchers to gain valuable insights into the regulatory mechanisms and functional implications of this post-translational modification.

Furthermore, this antibody demonstrates exceptional sensitivity, enabling the detection of even low levels of phosphorylated Daxx protein. This sensitivity is crucial for the accurate quantification of phosphorylation levels and the detection of subtle changes in Daxx phosphorylation under different experimental conditions.

The Daxx(Phospho Ser668) Polyclonal Antibody has been extensively validated in various cell lines and tissues, ensuring its reliability and reproducibility across different experimental setups. Its robust performance and consistent results make it an ideal choice for researchers studying Daxx phosphorylation and its role in cellular processes, such as apoptosis, DNA damage response, and transcriptional regulation.

In summary, the Daxx(Phospho Ser668) Polyclonal Antibody is a highly specific, sensitive, and reliable tool for the detection and quantification of phosphorylated Daxx protein. Its exceptional performance and versatility make it an invaluable asset for researchers aiming to unravel the intricate mechanisms underlying Daxx phosphorylation and its functional implications.