DHI2 Polyclonal Antibody

There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor. In tissues that do not express the mineralocorticoid receptor, such as the placenta and testis, it protects cells from the growth-inhibiting and/or pro-apoptotic effects of cortisol, particularly during embryonic development. Mutations in this gene cause the syndrome of apparent mine

The DHI2 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of DHI2 protein expression. This antibody has been meticulously developed using advanced techniques to ensure exceptional sensitivity and accuracy in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

With its exceptional affinity and specificity, the DHI2 Polyclonal Antibody enables researchers to confidently investigate the role and function of DHI2 in various biological processes. It exhibits minimal cross-reactivity with other proteins, ensuring precise and reliable results.

The DHI2 Polyclonal Antibody is produced using high-quality materials and undergoes rigorous quality control measures to guarantee consistent performance and reproducibility. It is supplied as a liquid formulation, allowing for easy handling and convenient storage.

This antibody is suitable for use in diverse research areas, including cancer biology, developmental biology, and neurobiology. Its versatility and reliability make it an indispensable tool for scientists and researchers seeking to unravel the complexities of DHI2 protein expression and its implications in various physiological and pathological conditions.

Choose the DHI2 Polyclonal Antibody for its exceptional specificity, reliability, and versatility, and unlock new insights into the intricate mechanisms governed by DHI2 protein expression.