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ELK Biotechnology
SKU(재고 관리 코드):ES2179
DMGDH Rabbit Polyclonal Antibody
DMGDH Rabbit Polyclonal Antibody
DMGDH Rabbit Polyclonal Antibody
Overview
| Product name: | DMGDH rabbit pAb |
| Alternative Names: | DMGDH; Dimethylglycine dehydrogenase; mitochondrial; ME2GLYDH |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human DMGDH. AA range:817-866 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 97kD |
| GeneID(Human): | 29958 |
| Human Swiss-Prot No: | Q9UI17 |
| Cellular localization: | Mitochondrion. |
| Background: | This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013], |
| Species Reactivity: | Human;Rat;Mouse; |
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Western Blot analysis of various cells using DMGDH Polyclonal Antibody -
Western blot analysis of lysates from HT-29 and A549 cells, using DMGDH Antibody. The lane on the right is blocked with the synthesized peptide. -
Western blot analysis of the lysates from HeLa cells using DMGDH antibody. -
Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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