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ELK Biotechnology

SKU(재고 관리 코드):ES2179

DMGDH Rabbit Polyclonal Antibody

DMGDH Rabbit Polyclonal Antibody

Size

DMGDH Rabbit Polyclonal Antibody

Overview

Product name: DMGDH rabbit pAb
Alternative Names: DMGDH; Dimethylglycine dehydrogenase; mitochondrial; ME2GLYDH
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human DMGDH. AA range:817-866
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 97kD
GeneID(Human): 29958
Human Swiss-Prot No: Q9UI17
Cellular localization: Mitochondrion.
Background: This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Species Reactivity: Human;Rat;Mouse;
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