DNA pol beta (Acetyl Lys72) Rabbit Polyclonal Antibody

Catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).|cofactor:Binds 2 magnesium ions per subunit.|Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity.|Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.|PTM:Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.|Belongs to the DNA polymerase type-X family.|subunit:Monomer.|

The DNA pol beta (Acetyl Lys72) Rabbit Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of DNA polymerase beta (pol beta) protein in various biological samples. This antibody has been raised in rabbits and purified using advanced techniques to ensure high affinity and specificity.

DNA polymerase beta is a key enzyme involved in DNA repair and replication processes. The acetylation of Lys72 residue in pol beta has been shown to play a crucial role in its enzymatic activity and regulation. This antibody specifically recognizes the acetylated form of Lys72 in pol beta, allowing for the precise detection and quantification of this modified protein.

The DNA pol beta (Acetyl Lys72) Rabbit Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable results.

This antibody is supplied as a liquid formulation in a convenient size of 100 µg. It is provided in a ready-to-use format, eliminating the need for any additional preparation steps. The antibody has been rigorously tested for its stability and quality, ensuring consistent performance over time.

In summary, the DNA pol beta (Acetyl Lys72) Rabbit Polyclonal Antibody is a valuable tool for researchers studying DNA repair and replication processes. Its high specificity, sensitivity, and convenience make it an ideal choice for various applications in molecular biology and biochemistry.