Dok-4 Polyclonal Antibody

The downstream of kinase family (Dok-1-7) are members of a class of docking proteins that interact with receptor tyrosine kinases and, via this interaction, mediate biological responses within the body. Dok-4 (Downstream of kinase-4) is a 326 amino acid protein that contains one PH domain and one IRS-type PTB domain and belongs to the Dok family of interacting proteins. Expressed in a variety of tissues with highest expression in liver, heart, kidney and skeletal muscle, Dok-4 plays an important role in Ret-mediated neurite outgrowth and may link Ret with downstream effectors during neuronal differentiation. Additionally, Dok-4 is thought to play a positive role in the activation of MAPK pathways and may participate in T-cell induced immune system regulation. Overexpression of Dok-4 is associated with clear cell renal cell carcinoma, suggesting a role for Dok-4 in tumorigenesis.

The Dok-4 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Dok-4 protein expression in various biological samples. This antibody has been meticulously developed and validated to ensure exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The Dok-4 Polyclonal Antibody exhibits exceptional sensitivity and specificity, enabling accurate and precise quantification of Dok-4 protein levels. It has been rigorously tested to ensure minimal cross-reactivity with other proteins, ensuring reliable and reproducible results.

This antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. It is manufactured under strict quality control measures to guarantee optimal performance and reliability. Each batch is thoroughly tested to meet the highest standards of quality, ensuring consistent and reproducible results.

The Dok-4 Polyclonal Antibody is supplied as a liquid formulation, making it convenient and easy to use. It is provided in a ready-to-use format, eliminating the need for time-consuming and error-prone reconstitution steps. The antibody is stable and can be stored at recommended temperatures for extended periods without compromising its performance.

With its exceptional specificity, sensitivity, and reliability, the Dok-4 Polyclonal Antibody is an indispensable tool for researchers and scientists studying Dok-4 protein expression and its role in various biological processes. Its high-quality formulation and performance make it an ideal choice for a wide range of applications, enabling accurate and reliable data generation.