eIF4B(Phospho Ser422) Polyclonal Antibody

Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.,Contains 1 RRM (RNA recognition motif) domain.,subunit:Self-associates and interacts with EIF3 p170 subunit.,

The eIF4B(Phospho Ser422) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of eIF4B protein phosphorylated at Ser422. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

eIF4B is a crucial regulator of translation initiation, playing a vital role in the recruitment of ribosomes to mRNA. Phosphorylation of eIF4B at Ser422 has been shown to enhance its activity, leading to increased translation efficiency. Therefore, the detection and analysis of eIF4B phosphorylation at Ser422 are of great importance in understanding the intricate mechanisms of protein synthesis.

The eIF4B(Phospho Ser422) Polyclonal Antibody exhibits exceptional specificity, binding only to the phosphorylated form of eIF4B at Ser422. This antibody has been extensively validated through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence. It demonstrates minimal cross-reactivity with non-phosphorylated eIF4B and other related proteins, ensuring accurate and reliable results.

With its high sensitivity, this antibody allows for the detection of even low levels of phosphorylated eIF4B, making it an ideal tool for both qualitative and quantitative analysis. Its robust performance and reproducibility make it suitable for a wide range of applications, including basic research, drug discovery, and clinical diagnostics.

The eIF4B(Phospho Ser422) Polyclonal Antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and saving valuable time in the laboratory. It is available in various sizes to accommodate different experimental needs.

In summary, the eIF4B(Phospho Ser422) Polyclonal Antibody is a reliable and specific tool for the detection and quantification of phosphorylated eIF4B at Ser422. Its high sensitivity, exceptional specificity, and robust performance make it an invaluable asset for researchers and scientists in the field of protein synthesis and translation regulation.