ELOVL1; SSC1; CGI-88; Elongation of very long chain fatty acids protein 1; 3-keto acyl-CoA synthase ELOVL1; ELOVL fatty acid elongase 1; ELOVL FA elongase 1
Applications:
WB;IHC;IF;ELISA
Recommended Dilutions:
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen:
The antiserum was produced against synthesized peptide derived from human ELOVL1. AA range:101-150
Storage:
-20°C/1 year
Storage:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
35kD
GeneID（Human）:
64834
Human Swiss-Prot No:
Q9BW60
Cellular localization:
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Background:
domain:The di-lysine motif confers endoplasmic reticulum localization for type I membrane proteins.,function:Could be implicated in tissue-specific synthesis of very long chain fatty acids and sphingolipids. May catalyze one or both of the reduction reaction in fatty acid elongation, i.e., conversion of beta-ketoacyl CoA to beta-hydroxyacyl CoA or reduction of trans-2-enoyl CoA to the saturated acyl CoA derivative.,similarity:Belongs to the ELO family.,
Western Blot analysis of various cells using ELOVL1 Polyclonal Antibody diluted at 1:1000
Immunohistochemical analysis of paraffin-embedded Human skeletal muscle. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-abs
Western blot analysis of lysates from Jurkat and HepG2 cells, using ELOVL1 Antibody. The lane on the right is blocked with the synthesized peptide.