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ELK Biotechnology
SKU(재고 관리 코드):EM1083
IDE/Insulin Degrading Enzyme Mouse mAb
IDE/Insulin Degrading Enzyme Mouse mAb
Applications: WB, IHC
Reactivity: Human
Source: Mouse
Dilution: WB 1:1,000 IHC 1:200
Immunogen: Synthetic Peptide
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed_band(KD): 118kDa
Human_gene_id: 3416
Human_swiss_prot_no: P14735
Subcellular_location: Cell membrane, Cytoplasm, Membrane, Secreted
Other_name: Abeta degrading protease, insulin degrading enzyme, Insulin protease, Insulinase, INSULYSIN
Background: Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently.
Reactivity: Human
Source: Mouse
Dilution: WB 1:1,000 IHC 1:200
Immunogen: Synthetic Peptide
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed_band(KD): 118kDa
Human_gene_id: 3416
Human_swiss_prot_no: P14735
Subcellular_location: Cell membrane, Cytoplasm, Membrane, Secreted
Other_name: Abeta degrading protease, insulin degrading enzyme, Insulin protease, Insulinase, INSULYSIN
Background: Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently.
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