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ELK Biotechnology

SKU(재고 관리 코드):EM1373

NBR1 (7C3) Mouse mAb

NBR1 (7C3) Mouse mAb

Size
Applications: IHC
Reactivity: Human, Mouse, Rat
Source: Mouse
Dilution: IHC 1:100-200
Immunogen: Recombinant Protein
Storage_stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Monoclonal
Isotype: IgG1
Concentration: 1mg/mL
Observed_band(KD): 120kDa
Human_gene_id: 4077
Human_swiss_prot_no: Q14596
Subcellular_location: Cytoplasm, Cytoplasmic vesicle, Lysosome
Other_name: 1A13B, MIG19, Nbr1
Background: NBR1 protein is known for its encoding gene proximity to the BRCA1 tumor suppressor gene. N-terminal Phox and Bem1p (PB1) domains of NBR1 mediate its interaction with muscle specific titin kinase and scaffolding protein p62. NBR1 plays a role in autophagy by facilitating the autophagosomal degradation of ubiquitinated proteins independently and also in concert with p62.
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