EMR2 (Cleaved-Leu517) Rabbit Polyclonal Antibody

This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

The EMR2 (Cleaved-Leu517) Rabbit Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of EMR2 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the cleaved Leu517 region of the EMR2 protein. The antibody has been purified using protein A affinity chromatography and is supplied as a liquid solution in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

The EMR2 protein is a member of the adhesion G protein-coupled receptor (GPCR) family and is involved in various cellular processes, including cell adhesion, migration, and immune response. The cleaved Leu517 region of the EMR2 protein is a specific epitope that is exposed on the cell surface and can be targeted by this antibody.

This rabbit polyclonal antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and flow cytometry. It has been shown to specifically recognize the cleaved Leu517 region of the EMR2 protein and does not cross-react with other related proteins.

Overall, the EMR2 (Cleaved-Leu517) Rabbit Polyclonal Antibody is a reliable and high-quality tool for the detection and analysis of EMR2 protein in various biological samples. Its high specificity and sensitivity make it an ideal choice for researchers studying the role of EMR2 in various cellular processes and diseases.