Ephrin-B3 Polyclonal Antibody

EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. Moreover, since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH Receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.

The Ephrin-B3 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Ephrin-B3 protein expression in various biological samples. This antibody has been extensively validated for its exceptional performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) applications.

The Ephrin-B3 Polyclonal Antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. It exhibits a strong affinity towards Ephrin-B3, enabling precise and accurate detection of this protein in both research and clinical settings.

This antibody offers exceptional sensitivity and specificity, allowing for the detection of even low levels of Ephrin-B3 expression. Its robust performance ensures reliable and reproducible results, making it an ideal choice for various experimental and diagnostic applications.

The Ephrin-B3 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy handling and storage. The antibody is compatible with a wide range of sample types, including tissue sections, cell lysates, and whole-cell extracts.

With its exceptional performance and versatility, the Ephrin-B3 Polyclonal Antibody is an invaluable tool for researchers and clinicians studying Ephrin-B3 protein expression and its role in various biological processes. Its reliable and accurate results make it an essential component of any laboratory or diagnostic facility.