ER alpha(Phospho Ser106) Polyclonal Antibody

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

The ER alpha(Phospho Ser106) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated Ser106 of the estrogen receptor alpha (ER alpha) protein. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target epitope.

The ER alpha protein plays a crucial role in mediating estrogen signaling and is involved in various physiological processes, including development, reproduction, and homeostasis. Phosphorylation of Ser106 has been shown to modulate the activity and function of ER alpha, making it an important post-translational modification to study.

This polyclonal antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of phosphorylated Ser106 of ER alpha in various sample types.

The ER alpha(Phospho Ser106) Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and complex antibody preparation procedures. It is compatible with a wide range of experimental conditions and can be used in both research and clinical settings.

With its exceptional performance and reliability, the ER alpha(Phospho Ser106) Polyclonal Antibody is an indispensable tool for researchers and clinicians studying the role of ER alpha phosphorylation in estrogen signaling and related biological processes.