CD340, HER 2/neu, HER2, MLN 19, MLN19, NEU, NGL, p185, p185erbB2, Proto oncogene c ErbB 2, Proto oncogene Neu, TKR1
Source:
Mouse
Applications:
WB, IHC
Species:
Human
Recommended dilutions:
WB 1:1,000 IHC 1:200-500
Immunogen:
Synthetic Peptide
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality:
Monoclonal
Isotype:
IgG1
Concentration:
1mg/ml
Observed band:
138kDa
GeneID（Human）:
2064
Human Swiss-Prot No:
P04626
Cellular localization:
Cytoplasm. Nucleus and Cell membrane
Background:
ErbB 2 is a receptor tyrosine kinase of the ErbB 2 family. It is closely related instructure to the epidermal growth factor receptor. ErbB 2 oncoprotein is detectable in a proportion of breast and other adenocarconomas, as well as transitional cell carcinomas. In the case of breast cancer, expression determined by immunohistochemistry has been shown to be associated with poor prognosis.
