ERK 1/2(Phospho Thr202/Y204) Polyclonal Antibody

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.

The ERK 1/2 (Phospho Thr202/Y204) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated ERK 1/2 proteins. This antibody is produced using advanced techniques and high-quality materials to ensure optimal performance and reliability.

The ERK 1/2 pathway plays a crucial role in various cellular processes, including cell proliferation, differentiation, and survival. The phosphorylation of ERK 1/2 at Thr202 and Tyr204 residues is a key event in the activation of this pathway. Therefore, the detection and quantification of phosphorylated ERK 1/2 proteins are essential for understanding their functional roles in cellular signaling.

This polyclonal antibody has been extensively validated for its specificity and sensitivity in various experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated ERK 1/2 proteins, ensuring accurate and reliable results.

The ERK 1/2 (Phospho Thr202/Y204) Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, allowing for easy handling and storage. The antibody is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.

With its exceptional performance and versatility, the ERK 1/2 (Phospho Thr202/Y204) Polyclonal Antibody is an indispensable tool for researchers and scientists studying cellular signaling pathways and their implications in various biological processes. Its high specificity, sensitivity, and reliability make it an ideal choice for accurate and reproducible results in both basic and clinical research applications.