DNER rabbit pAb

Applications: WB;ELISA
Reactivity: Human;Mouse
Source: Rabbit
Dilution: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 81kD
Human_gene_id: 92737
Human_swiss_prot_no: Q8NFT8
Subcellular_location: Cell membrane; Single-pass type I membrane protein. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity). .
Background: function:Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.,similarity:Contains 1 follistatin-like domain.,similarity:Contains 10 EGF-like domains.,subcellular location:Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region.,subunit:Interacts with AP1G1. Interacts with NOTCH1.,tissue specificity:Expressed in brain, spinal cord and adrenal gland.,