PRAS40 (phospho-Ser183) rabbit pAb

Applications: WB;ELISA;IHC
Reactivity: Human;Mouse
Source: Rabbit
Dilution: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: Synthesized phosho peptide around human PRAS40 (Ser183)
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 40kD
Human_gene_id: 84335
Human_swiss_prot_no: Q96B36
Subcellular_location: Cytoplasm, cytosol . Found in the cytosolic fraction of the brain. .
Other_name: Proline-rich AKT1 substrate 1 (40 kDa proline-rich AKT substrate)
Background: AKT1S1 is a proline-rich substrate of AKT (MIM 164730) that binds 14-3-3 protein (see YWHAH, MIM 113508) when phosphorylated (Kovacina et al., 2003 [PubMed 12524439]).[supplied by OMIM, Mar 2008],