PDE6G Rabbit pAb

Applications: IHC; ELISA
Reactivity: Human; Mouse
Source: Rabbit
Dilution: IHC-p 1:50-200, ELISA(peptide)1:5000-20000
Immunogen: Synthesized peptide derived from human PDE6G AA range: 10-90
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 5148
Human_swiss_prot_no: P18545
Subcellular_location: plasma membrane,photoreceptor disc membrane,
Other_name: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (GMP-PDE gamma;EC 3.1.4.35)
Background: This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009],