DOLK rabbit pAb

Applications: WB
Reactivity: Human; Mouse
Source: Rabbit
Dilution: WB 1：500-2000
Immunogen: Synthesized peptide derived from human DOLK AA range: 420-470
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Human_gene_id: 22845
Human_swiss_prot_no: Q9UPQ8
Subcellular_location: Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Background: The protein encoded by this gene catalyzes the CTP-mediated phosphorylation of dolichol, and is involved in the synthesis of Dol-P-Man, which is an essential glycosyl carrier lipid for C- and O-mannosylation, N- and O-linked glycosylation of proteins, and for the biosynthesis of glycosyl phosphatidylinositol anchors in endoplasmic reticulum. Mutations in this gene are associated with dolichol kinase deficiency.[provided by RefSeq, Apr 2010],