GABA A Receptor α2 rabbit pAb

Applications: WB;IHC;IF
Reactivity: Human;Rat;Mouse
Source: Rabbit
Dilution: WB 1:1000-2000, IHC 1:100-200
Immunogen: Synthetic Peptide of GABA A Receptor α2
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 51kD
Human_gene_id: 282236
Human_swiss_prot_no: P47869
Subcellular_location: Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane . Cell projection, dendrite .
Other_name: Gamma-aminobutyric acid receptor subunit alpha-2 (GABA(A) receptor subunit alpha-2)
Background: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013],