1
/
의
1
ELK Biotechnology
SKU(재고 관리 코드):ES20834
AMPKβ2 rabbit pAb
AMPKβ2 rabbit pAb
가격·납기 및 기술자료를 확인해 드립니다.
제품 규격과 수량을 선택한 후 견적을 요청해 주세요. 대체품 검토와 SDS·COA·데이터시트 요청도 함께 접수할 수 있습니다.
이 제품 견적 요청대표번호 070-8028-3500 · info@rndmate.com
Applications: WB
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB: 1:1000-2000
Immunogen: Recombinant Protein of AMPKβ2
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Observed_band(KD): 30kD
Human_gene_id: 5565
Human_swiss_prot_no: O43741
Subcellular_location: nucleoplasm,cytosol,nucleotide-activated protein kinase complex,
Other_name: PRKAB2; 5'-AMP-activated protein kinase subunit beta-2; AMPK subunit beta-2
Background: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013],
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB: 1:1000-2000
Immunogen: Recombinant Protein of AMPKβ2
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Observed_band(KD): 30kD
Human_gene_id: 5565
Human_swiss_prot_no: O43741
Subcellular_location: nucleoplasm,cytosol,nucleotide-activated protein kinase complex,
Other_name: PRKAB2; 5'-AMP-activated protein kinase subunit beta-2; AMPK subunit beta-2
Background: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013],
Share
