SLK rabbit pAb

Applications: WB;IHC;IF;ELISA
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human SLK. AA range:1151-1200
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 150kD
Human_gene_id: 9748
Human_swiss_prot_no: Q9H2G2
Subcellular_location: Cytoplasm .
Other_name: SLK; KIAA0204; STK2; STE20-like serine/threonine-protein kinase; STE20-like kinase; hSLK; CTCL tumor antigen se20-9; STE20-related serine/threonine-protein kinase; STE20-related kinase; Serine/threonine-protein kinase 2
Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Mediates apoptosis and actin stress fiber dissolution.,PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM:Proteolytically cleaved by caspase-3.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 422.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 611.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 614.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UVR domain.,tissue specificity:Ubiquitously expressed. Highest expression is found in heart and in skeletal muscle.,