FA11 Rabbit Polyclonal Antibody

This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen| which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI| an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains| resulting in activated factor XIa| a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome| a blood coagulation abnormality.

The FA11 Rabbit Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the target protein. The resulting polyclonal antibody exhibits high affinity and specificity towards the target protein, making it an ideal tool for detecting and quantifying the protein of interest in various biological samples.

The FA11 Rabbit Polyclonal Antibody has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to provide reliable and reproducible results, with minimal background noise and cross-reactivity with other proteins.

This antibody is supplied as a purified IgG fraction, which has been affinity-purified from rabbit serum. It is provided in a convenient format, with a concentration of 1 mg/mL, making it easy to use in a variety of experimental settings.

Overall, the FA11 Rabbit Polyclonal Antibody is a high-quality reagent that offers exceptional performance and versatility for a wide range of research applications. Its high specificity and sensitivity make it an essential tool for researchers studying the target protein in various biological systems.