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SKU(재고 관리 코드):LAA785Hu81

FITC-Linked Polyclonal Antibody to Kidney Injury Molecule 1 (Kim1)

FITC-Linked Polyclonal Antibody to Kidney Injury Molecule 1 (Kim1)

UOM
Concentration
Organism species

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

Product No.

LAA785Hu81

Organism Species

Homo sapiens (Human).

Source

Antibody labeling

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

FITC

Original Antibody

n/a

Buffer Formulation

PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Traits

Liquid

Concentration

500µg/mL

Organism Species More

n/a

Applications

WB; IHC; ICC; IF.

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against Kim1. It has been selected for its ability to recognize Kim1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

Clinical Toxicology

Clinical implication of urinary neutrophil gelatinase-associated lipocalin and kidney injury molecule-1 in patients with acute paraquat intoxication PubMed: 19827907

Pediatric Nephrology

KIM-1 and NGAL: new markers of obstructive nephropathy SpringerLink: v461592787w5488x

Pediatric Research

Urinary Neutrophil Gelatinase-Associated Lipocalin at Birth Predicts Early Renal Function in Very Low Birth Weight Infants LWW: 10000

Archives of Medical Science

Markers of kidney function in the elderly in relation to the new CKD-EPI formula for estimation of glomerular filtration rate AMS: source

Nephrology

Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content PubMed: 23046363

Nanotoxicology.

Comprehensive assessment of nephrotoxicity of intravenously administered sodium-oleate-coated ultra-small superparamagnetic iron oxide (USPIO) and titanium dioxide (TiO(2)) nanoparticles in rats. PubMed: 23272807

Toxicological Science

A Mouse Diversity Panel Approach Reveals the Potential for Clinical Kidney Injury Due to DB289 Not Predicted by Classical Rodent Models PubMed: PMC3498743

Disease Markers

Interleukin 18 as a Marker of Chronic Nephropathy in Children after Anticancer Treatment Hindawi: 369784

Journal of Biomarkers

Urinary Measurement of Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 Helps Diagnose Acute Pyelonephritis in a Preclinical Model Hindawi: 413853

Advances in Life Science and Technology

Kidney injury molecule-1: a urinary biomarker for contrast induced acute kidney injury. Iiste: Source

Nephrology

Urinary neutrophil gelatinase-associated lipocalin predicts graft loss after acute kidney injury in kidney transplant Pubmed: 24325180

Nephrology

Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content. Pubmed: 23046363

BioMed Research International

The Renal Effects of Vanadate Exposure: Potential Biomarkers and Oxidative Stress as a Mechanism of Functional Renal Disorders—Preliminary Studies Hindawi: 740105

Life Sci.

Attenuation of renal ischemia/reperfusion injury by a?aí extract preconditioning in a rat model Pubmed:25476829

Diabetes & Vascular Disease Research

Urinary Kim-1 is a sensitive biomarker for the early stage of diabetic nephropathy in Otsuka Long-Evans Tokushima Fatty rats Sagepub:Source

临床儿科杂志

中性粒细胞明胶酶相关脂质运载蛋白、肾损伤分子1和白介素18 在诊断心肺分流术后急性肾损伤中的意义 Jcp-Sh:Source

Nephrology (Carlton).

Tubular urinary biomarkers do not identify aetiology of acute kidney injury in kidney transplant recipients Pubmed:24666430

PLoS One.

Cilostazol Renoprotective Effect: Modulation of PPAR-γ, NGAL, KIM-1 and IL-18 Underlies Its Novel Effect in a Model of Ischemia-Reperfusion Pubmed:24816434

BMC Nephrology

SYNbiotics Easing Renal failure by improving Gut microbiologY (SYNERGY): a protocol of placebo-controlled randomised cross-over trial Pubmed:24996842

Pediatric Nephrology

The diagnosis of febrile urinary tract infection in children may be facilitated by urinary biomarkers Pubmed:25127917

Inflammation.?

Systemic and Flap Inflammatory Response Associates with Thrombosis in Flap Venous Crisis Pubmed:25448261

Transworld Medical Journal

Kidney injury molecule-1: A urinary biomarker for contrast-induced acute kidney injury Tmjournals:Source

Int J Clin Exp Pathol

Rosiglitazone attenuates renal injury caused by hyperlipidemic pancreatitis PubMed: 26191125

Int J Clin Exp Pathol

Inhalation of hydrogen gas ameliorates glyoxylate-induced calcium oxalate deposition and renal oxidative stress in mice PubMed: 26045773

Mol Med Rep

Vorinostat protects against calcium oxalate-induced kidney injury in mice PubMed: 26095064

Pediatr Nephrol

Role of new biomarkers for predicting renal scarring in vesicoureteral reflux: NGAL, KIM-1, and L-FABP PubMed: 26324091

Journal of Pediatric Urology

Urinary NGAL, KIM-1 and L-FABP concentrations in antenatal hydronephrosis PubMed: 26096437

Am J Physiol Renal Physiol

Intrarenal Renin-Angiotensin System Mediates Fatty Acid-Induced ER Stress in the Kidney PubMed: 26672616

Mol Med Rep.

Attenuation of renal ischemia/reperfusion injury by oleanolic acid preconditioning via its antioxidant, anti‑inflammatory, and anti‑apoptotic activities. Pubmed:27082705

Nephrol. Dial. Transplant.

Preconditioned suppression of prolyl-hydroxylases attenuates renal injury but increases mortality in septic murine models Pubmed:26908768

J Clin Lab Anal. 

Kidney Injury Molecule Levels in Type 2 Diabetes Mellitus Pubmed:27132791

Med Sci Monit.

Protective Effect of Dihydromyricetin Against Lipopolysaccharide-Induced Acute Kidney Injury in a Rat Model pmc:PMC4754091

Diabetes.

Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis Pubmed:26822084

Sci Rep.

Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice Pubmed:27226136

Journal of Applied Life Sciences International

Vitamins C and E Alleviate Nephrotoxicity-induced by Potassium Bromate in Rats Barakat812016JALSI28698.pdf

Oxidative Medicine and Cellular Longevity

Synergic Effect of α-Mangostin on the Cytotoxicity of Cisplatin in a Cervical Cancer Model. pubmed:28053694

Molecular Medicine Reports

Attenuation of renal ischemia/reperfusion injury by oleanolic acid preconditioning via itsantioxidant, anti‑inflammatory, and anti‑apoptotic activities. pubmed:27082705

Journal of Agricultural and Food Chemistry

Protective Effects of DHA-PC against Vancomycin-Induced Nephrotoxicity through the Inhibition of Oxidative Stress and Apoptosis in BALB/c Mice pubmed:29254330

Clin Exp Pharmacol Physiol.

Early urinary biomarkers of renal tubular damage by a high-salt intake independent of blood pressure in normotensive rats. pubmed:29027259

Nephron - Physiology

Urinary Kidney Injury Molecule-1 but Not Urinary Neutrophil Gelatinase Associated Lipocalin Is Increased after Short Maximal Exercise 10.1159/000481179

Cellular Physiology and Biochemistry

Gum Acacia Improves Renal Function and Ameliorates Systemic Inflammation, Oxidative and Nitrosative Stress in Streptozotocin-Induced Diabetes in Rats … Pubmed:29550811

Frontiers in Pharmacology

Exploring the therapeutic mechanism of Desmodium styracifolium on oxalate crystal-induced kidney injuries using comprehensive approaches based on … Pubmed:29950996

Molecules

Effect of Pinocembrin Isolated from Mexican Brown Propolis on Diabetic Nephropathy Pubmed:29642511

American Journal of Physiology-Regulatory Integrative and Comparative Physiology

Modeling heart failure risk in diabetes and kidney disease: limitations and potential applications of transverse aortic constriction in high-fat-fed mice Pubmed:29443547

Biological Trace Element Research

Effect of Aqueous Extract of Glycyrrhiza glabra on the Biochemical Changes Induced by Cadmium Chloride in Rats Pubmed: 30251228

Cancer Research and Treatment

A Phage Display-Identified Peptide Selectively Binds to Kidney Injury Molecule-1(KIM-1) and Detects KIM-1-Overexpressing Tumors in vivo

Archives of Medical Science

Urinary neutrophil gelatinase-associated lipocalin, kidney injury molecule-1, N-acetyl-β-D-glucosaminidase levels and mortality risk in septic patients with … Pubmed: 30393493

Biological & Pharmaceutical Bulletin

UPLC/MS-Based Metabolomics Investigation of the Protective Effect of Hydrogen Gas Inhalation on Mice with Calcium Oxalate-Induced Renal Injury Pubmed: 30381664

Kidney and Blood Pressure Research

The Kidney Specific Protein myo-Inositol Oxygenase, a Potential Biomarker for Diabetic Nephropathy Pubmed: 30504713

Clinica Chimica Acta

Urine markers of renal tubular injury in idiopathic membranous nephropathy: A cross sectional study Pubmed: 30684459

BMC Complementary and Alternative Medicine

Dual actions on gout flare and acute kidney injury along with enhanced renal transporter activities by Yokuininto, a Kampo medicine Pubmed: 30871515

2.583

Application of ELISA Technique and Human Microsomes in the Search for 11β-Hydroxysteroid Dehydrogenase Inhibitors Doi: BioMed Research International

Naunyn-Schmiedeberg's archives of pharmacology

Piceatannol protects against cisplatin nephrotoxicity via activation of Nrf2/HO-1 pathway and hindering NF-κB inflammatory cascade Pubmed: 31197431

Egyptian Journal of Zoology

Effect of Cucumis melo var. flexuosus leaves extract on renal oxidative injury and inflammation in diabetic male albino rats

Environment International

Toxicity assessment due to prenatal and lactational exposure to lead, cadmium and mercury mixtures Pubmed: 31639605

Bioscience Reports

page Metabolomics study of fasudil on cisplatin-induced kidney injury Pubmed: 31670380

life sciences

MiR-214-3p exacerbates kidney damages and inflammation induced by hyperlipidemic pancreatitis complicated with acute renal injury Pubmed: 31790686

Arch Physiol Biochem

Protective effect of saxagliptin against renal ischaemia reperfusion injury in rats Pubmed: 31979992

clinical science

Delineating a role for the Mitochondrial Permeability Transition Pore in Diabetic Kidney Disease by targeting Cyclophilin D Pubmed: 31943002

LIFE SCIENCES

Rapamycin improves renal injury induced by Iodixanol in diabetic rats by deactivating the mTOR/p70S6K signaling pathway Pubmed: 32798557

INTERNATIONAL UROLOGY AND NEPHROLOGY

Serum NGAL, KIM-1, IL-18, L-FABP: new biomarkers in the diagnostics of acute kidney injury (AKI) following invasive cardiology procedures Pubmed: 32557377

Journal of Pediatric Urology

Can Serum Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 Help in Decision Making for Surgery in Antenatally Dedected … Pubmed: 33139211


Ratlarda sodyum florid ile oluşturulan toksikasyonda Karvakol'ün böbrekler üzerine etkisi


Rationale and design of the intervention in PHOspholamban RElated CArdiomyopathy STudy (i-PHORECAST)

Pediatr Int

Early Kidney Injury in Immunoglobulin A Vasculitis: Role of Renal Biomarkers 33423326

J Int Med Res

Value of urinary kidney injury molecule-1 levels in predicting acute kidney injury in very low birth weight preterm infants 33372811

Biomed Res Int

Renal Protective Effect of Beluga Lentil Pretreatment for Ischemia-Reperfusion Injury 33604384

Nutrients

Targeting Methylglyoxal in Diabetic Kidney Disease Using the Mitochondria-Targeted Compound MitoGamide 33922959

J Am Soc Nephrol

Kim-1 Targeted Extracellular Vesicles: A New Therapeutic Platform for RNAi to Treat AKI 34127536

Heliyon

Anti-oxidant impact of Lisinopril and Enalapril against acute kidney injury induced by doxorubicin in male Wistar rats: involvement of kidney injury molecule-1 33506137

Journal of Pharmacological Sciences

Pentoxifylline treatment alleviates kidney ischemia/reperfusion injury: Novel involvement of galectin-3 and ASK-1/JNK & ERK1/2/NF-¦ÊB/HMGB-1 trajectories 34030796

Int Urol Nephrol

Could urinary kidney injury molecule-1 be a good marker in subclinical acute kidney injury in mild to moderate COVID-19 infection? 34213713

Intensive Care Medicine Experimental

Preservation of renal endothelial integrity and reduction of renal edema by aprotinin does not preserve renal perfusion and function following experimental … 34169407

iscience

Kidney disease risk factors do not explain impacts of low dietary protein on kidney function and structure 34820603


Catalog No.

Related products for research use of Homo sapiens (Human) Organism species

Applications (RESEARCH USE ONLY!)

RPA785Hu01

Recombinant Kidney Injury Molecule 1 (Kim1)

Positive Control; Immunogen; SDS-PAGE; WB.

RPA785Hu02

Recombinant Kidney Injury Molecule 1 (Kim1)

Positive Control; Immunogen; SDS-PAGE; WB.

RPA785Hu03

Recombinant Kidney Injury Molecule 1 (Kim1)

Positive Control; Immunogen; SDS-PAGE; WB.

PAA785Hu01

Polyclonal Antibody to Kidney Injury Molecule 1 (Kim1)

WB; IHC; ICC; IP.

PAA785Hu02

Polyclonal Antibody to Kidney Injury Molecule 1 (Kim1)

WB; IHC; ICC; IP.

PAA785Hu03

Polyclonal Antibody to Kidney Injury Molecule 1 (Kim1)

WB; IHC; ICC; IP.

LAA785Hu81

FITC-Linked Polyclonal Antibody to Kidney Injury Molecule 1 (Kim1)

WB; IHC; ICC; IF.

LAA785Hu71

Biotin-Linked Polyclonal Antibody to Kidney Injury Molecule 1 (Kim1)

WB; IHC; ICC.

MAA785Hu22

Monoclonal Antibody to Kidney Injury Molecule 1 (Kim1)

WB

MAA785Hu21

Monoclonal Antibody to Kidney Injury Molecule 1 (Kim1)

WB; IHC; ICC; IP.

MAA785Hu23

Monoclonal Antibody to Kidney Injury Molecule 1 (Kim1)

IHC

MAA785Hu24

Monoclonal Antibody to Kidney Injury Molecule 1 (Kim1)

WB; IHC; ICC; IP.

SEA785Hu

ELISA Kit for Kidney Injury Molecule 1 (Kim1)

Enzyme-linked immunosorbent assay for Antigen Detection.

SCA785Hu

CLIA Kit for Kidney Injury Molecule 1 (Kim1)

Chemiluminescent immunoassay for Antigen Detection.

LMA785Hu

Magnetic Luminex Assay Kit for Kidney Injury Molecule 1 (Kim1) ,etc.

Magnetic Luminex Assay for Antigen Detection.

PSA785Hu01

Antibody Pair for Kidney Injury Molecule 1 (Kim1)

ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays.

KSA785Hu01

ELISA Kit DIY Materials for Kidney Injury Molecule 1 (Kim1)

Main materials for "Do It (ELISA Kit) Yourself".

 

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