Cloud-clone
SKU(재고 관리 코드):LAA756Mu81
FITC-Linked Polyclonal Antibody to Mucin 5 Subtype AC (MUC5AC)
FITC-Linked Polyclonal Antibody to Mucin 5 Subtype AC (MUC5AC)
Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.
Product No.
LAA756Mu81
Organism Species
Mus musculus (Mouse).
Source
Antibody labeling
Ig Type
IgG
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Label
FITC
Original Antibody
n/a
Buffer Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Traits
Liquid
Concentration
500µg/mL
Organism Species More
n/a
Applications
WB; IHC; ICC; IF.
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against MUC5AC. It has been selected for its ability to recognize MUC5AC in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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Magazine |
Citations |
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Annals of surgical oncology |
Pancreatic cyst fluid and serum mucin levels predict dysplasia in intraductal papillary mucinous neoplasms of the pancreas. PubMed: 20717734 |
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Investigative Ophthalmology & Visual Science |
Entrapment of Conjunctival Goblet Cells by Desiccation-Induced Cornification PubMed: 21421863 |
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Cell & Molecular Biology |
Role of aquaporin 5 in antigen-induced airway inflammation and mucous hyperproduction in mice PubMed: 20550619 |
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Mucosal Immunology |
Homeostatic control of conjunctival mucosal goblet cells by NKT-derived IL-13 Nature: 201082a |
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European Journal of Pharmacology |
Naringin attenuates EGF-induced MUC5AC secretion in A549 cells by suppressing the cooperative activities of MAPKs-AP-1 and IKKs-IκB-NF-κB signaling pathways ScienceDirect: S0014299912005523 |
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PLoS One |
Baicalein Reduces Airway Injury in Allergen and IL-13 Induced Airway Inflammation PubMed: PMC3639905 |
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Respiratory Researh |
Pyocyanin-induced mucin production is associated with redox modification of FOXA2 PubMed: PMC3765780 |
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Surgery |
A novel serum marker for biliary tract cancer: Diagnostic and prognostic values of quantitative evaluation of serum mucin 5AC (MUC5AC) Pubmed: 24468034 |
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Biochemical and Biophysical Research Communications |
The human cathelicidin LL-37 enhances airway mucus production in chronic obstructive pulmonary disease Pubmed:24291709 |
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Journal of Proteomics |
Proteomic analysis of cancer and mesothelial cells reveals an increase in Mucin 5AC during ovarian cancer and peritoneal interaction Pubmed:24726482 |
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Experimental Lung Research |
The human Cathelicidin LL-37 induces MUC5AC mucin production by airway epithelial cells via TACE-TGF-α-EGFR pathway Pubmed:24901072 |
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Surgery.? |
Assessment of bile and serum mucin5AC in cholangiocarcinoma: Diagnostic performance and biologic significance Pubmed:25151557 |
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Allergology International |
Leukotriene E 4 induces MUC5AC release from human airway epithelial NCI-H292 cells Pubmed:25838093 |
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Respirology |
Secreted mucins and airway bacterial colonization in non-CF bronchiectasis PubMed: 26172851 |
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S |
Isabela Casagrande Jeremias Teses: Disponiveis |
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American Thoracic Society International Conference Abstracts |
Mucin Secretion In Asthmatics With Osmotic Airway Hyperresponsiveness doi:10.1164 |
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Deletion Polymorphism and Chronic Obstructive Pulmonary Disease |
ReCavia (Guinea pig )lation of Viral Infection-induced Airway Remodeling Cytokine Production by the TLR3-EGFR Signaling Pathway in Human Bronchial Epithelial Cells Pubmed:27075970 |
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Int J Clin Exp Med |
The influence of long-term corneal contact lens wearing on the stability and quality of tear film in Qinghai files:ijcem0020163.pdf |
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Ann Am Thorac Soc |
Airway Mucin 2 Is Decreased in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization doi:10.1513 |
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Sci Rep |
Impact of Cigarette Smoking on Tear Function and Correlation between Conjunctival Goblet Cells and Tear MUC5AC Concentration in Office Workers Pubmed:27297822 |
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Cytokine. |
Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasalepithelial cells. pubmed:27776277 |
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J Virol. |
Mutating the CX3C Motif in the G Protein Should Make a Live Respiratory Syncytial Virus Vaccine Safer and More Effective. pubmed:28275196 |
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Respiratory Physiology & Neurobiology |
Peroxiredoxin 6 suppresses Muc5ac overproduction in LPS-induced airway inflammation through H2O2-EGFR-MAPK signaling pathway. pubmed:27884794 |
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Journal of Immunology Research |
Beneficial effects of prebiotic Saccharomyces cerevisiae mannan on allergic asthma mouse models pubmed:28835901 |
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BASIC INVESTIGATION |
Efficacy of Sodium Hyaluronate in Murine Diabetic Ocular Surface Diseases pubmed:28644234 |
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International Immunopharmacology |
Clarithromycin inhibits TNF-α-induced MUC5AC mucin gene expression via the MKP-1-p38MAPK-dependent pathway pubmed:28550735 |
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Секреторно-экссудативная реакция слизистой носа на воздействие холодного воздуха у больных бронхиальной астмой 10.20538/1682-0363-2017-2-146-158 |
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Cellular Microbiology |
An adherent mucus layer attenuates the genotoxic effect of colibactin. pubmed:29156489 |
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Respiratory Research |
IL-4-induced caveolin-1-containing lipid rafts aggregation contributes to MUC5AC synthesis in bronchial epithelial cells pubmed:28931396 |
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Chemotherapy |
Oxytetracycline Inhibits Mucus Secretion and Inflammation in Human Airway Epithelial Cells. pubmed:28578323 |
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Allergy |
Th2 cytokines orchestrate the secretion of MUC 5 AC and MUC 5B in IL‐5 positive chronic rhinosinusitis with nasal polyps Pubmed:29802623 |
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European Journal of Pharmacology |
Salvianolic acid B improves airway hyperresponsiveness by inhibiting MUC5AC overproduction associated with Erk1/2/P38 signaling Pubmed:29382534 |
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Inflammation |
Plantamajoside Inhibits Lipopolysaccharide-Induced MUC5AC Expression and Inflammation through Suppressing the PI3K/Akt and NF-κB Signaling Pathways in … Pubmed:29349683 |
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Pulmonary Pharmacology and Therapeutics |
In vivo and in vitro investigation of anti-inflammatory and mucus-regulatory activities of a fixed combination of thyme and primula extracts Pubmed:29698781 |
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European Respiratory Society |
Profiling of healthy and asthmatic airway smooth muscle cells following IL-1β treatment: a novel role for CCL20 in chronic mucus hyper-secretion Pubmed:29946002 |
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Clinical and Experimental Ophthalmology |
Development of a highly sensitive and reliable enzyme-linked immunosorbent assay for MUC5aC in human tears extracted from schirmer strips Pubmed: 30214141 |
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international journal of biological macromolecules |
Increased expression of long non-coding RNA SNHG16 correlates with tumor progression and poor prognosis in non-small cell lung cancer Pubmed: 30287374 |
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Journal of Investigative Medicine |
The characteristics and clinical significance of mucin levels in bronchoalveolar lavage fluid of patients with interstitial lung disease Pubmed: 30573494 |
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Phytomedicine |
Regulation effects of naringin on diesel particulate matter-induced abnormal airway surface liquid secretion Pubmed: 31301536 |
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Scientific Reports |
Regional comparison of Goblet cell number and Area in exposed and covered Dry eyes and their Correlation with Tear MUC5AC Pubmed: 32076085 |
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Eur J Pharmacol |
TLR3 inhibitor and tyrosine kinase inhibitor attenuate cigarette smoke/poly I: C-induced airway inflammation and remodeling by the EGFR/TLR3/MAPK … Pubmed: 33068589 |
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journal of ethnopharmacology |
Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K … Pubmed: 32344236 |
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Less Airway Inflammation and Goblet Cell Metaplasia in an IL-33-Induced Asthma Model of Leptin-Deficient Obese Mice |
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Exp Mol Pathol |
The regulatory role of SFRP5/WNT5A axis in allergic rhinitis through inhibiting JNK pathway activation and lowering mucin generation in human nasal?¡ 33285209 |
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FEBS Open Bio |
Porphyromonas gingivalis gingipains potentially affect MUC5AC gene expression and protein levels in respiratory epithelial cells 33332733 |
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Cell Rep |
Generation of functional conjunctival epithelium, including goblet cells, from human iPSCs 33535050 |
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Catalog No. |
Related products for research use of Mus musculus (Mouse) Organism species |
Applications (RESEARCH USE ONLY!) |
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LAA756Mu81 |
FITC-Linked Polyclonal Antibody to Mucin 5 Subtype AC (MUC5AC) |
WB; IHC; ICC; IF. |
|
LAA756Mu71 |
Biotin-Linked Polyclonal Antibody to Mucin 5 Subtype AC (MUC5AC) |
WB; IHC; ICC. |
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IEA756Mu |
Enzyme-linked immunosorbent assay for Antigen Detection. |
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SEA756Mu |
Enzyme-linked immunosorbent assay for Antigen Detection. |
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SCA756Mu |
Chemiluminescent immunoassay for Antigen Detection. |
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LMA756Mu |
Magnetic Luminex Assay Kit for Mucin 5 Subtype AC (MUC5AC) ,etc. |
Magnetic Luminex Assay for Antigen Detection. |
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Main materials for "Do It (ELISA Kit) Yourself". |
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