Flk-1/VEGFR2(Phospho Tyr1059) Polyclonal Antibody

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

The Flk-1/VEGFR2(Phospho Tyr1059) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Flk-1/VEGFR2 protein phosphorylated at tyrosine 1059. This antibody is produced using advanced techniques and rigorous quality control measures to ensure optimal performance and reliability.

Flk-1/VEGFR2, also known as vascular endothelial growth factor receptor 2, plays a crucial role in angiogenesis and vascular development. Phosphorylation of tyrosine 1059 is a key event in the activation of Flk-1/VEGFR2 signaling pathway, which regulates various cellular processes including cell proliferation, migration, and survival.

The Flk-1/VEGFR2(Phospho Tyr1059) Polyclonal Antibody exhibits high affinity and specificity towards the phosphorylated form of Flk-1/VEGFR2 at tyrosine 1059. It has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size and concentration, ensuring cost-effectiveness and minimizing waste. The Flk-1/VEGFR2(Phospho Tyr1059) Polyclonal Antibody is compatible with a wide range of sample types, including cell lysates, tissue extracts, and cultured cells.

With its exceptional sensitivity and specificity, the Flk-1/VEGFR2(Phospho Tyr1059) Polyclonal Antibody is an indispensable tool for researchers and scientists studying angiogenesis, vascular biology, and related fields. Its reliable performance and consistent results make it an ideal choice for both basic research and clinical applications.

Order your Flk-1/VEGFR2(Phospho Tyr1059) Polyclonal Antibody today and unlock new insights into the intricate mechanisms of Flk-1/VEGFR2 signaling pathway.