Flk-1/VEGFR2(Phospho Tyr1175) Polyclonal Antibody

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

The Flk-1/VEGFR2(Phospho Tyr1175) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Flk-1/VEGFR2 protein phosphorylated at Tyr1175. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

Flk-1/VEGFR2, also known as vascular endothelial growth factor receptor 2, plays a crucial role in angiogenesis and vascular development. Phosphorylation of Tyr1175 residue is a key event in the activation of Flk-1/VEGFR2 signaling pathway, which regulates various cellular processes including cell proliferation, migration, and survival.

The Flk-1/VEGFR2(Phospho Tyr1175) Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of phosphorylated Flk-1/VEGFR2 protein in complex biological samples.

This antibody is supplied as a liquid formulation, ready to use for laboratory research purposes. It is recommended to store the antibody at -20°C for long-term stability. Each vial contains sufficient antibody for multiple experiments, ensuring cost-effectiveness and convenience.

In summary, the Flk-1/VEGFR2(Phospho Tyr1175) Polyclonal Antibody is a valuable tool for researchers studying angiogenesis, vascular development, and related signaling pathways. Its high specificity, sensitivity, and versatility make it an ideal choice for various experimental applications.