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ELK Biotechnology
SKU(재고 관리 코드):ES5415
Fyn (phospho Tyr530) Rabbit Polyclonal Antibody
Fyn (phospho Tyr530) Rabbit Polyclonal Antibody
Fyn (phospho Tyr530) Rabbit Polyclonal Antibody
Overview
| Product name: | Fyn (phospho Tyr530) rabbit pAb |
| Alternative Names: | FYN; Tyrosine-protein kinase Fyn; Proto-oncogene Syn; Proto-oncogene c-Fyn; Src-like kinase; SLK; p59-Fyn |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human Fyn around the phosphorylation site of Tyr530. AA range:488-537 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 60kD |
| GeneID(Human): | 2534 |
| Human Swiss-Prot No: | P06241 |
| Cellular localization: | Cytoplasm. Nucleus. Cell membrane. Present and active in lipid rafts. Palmitoylation is crucial for proper trafficking. |
| Background: | This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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Western Blot analysis of LOVO+UV cells using Phospho-Fyn (Y530) Polyclonal Antibody diluted at 1:2000 -
Western blot analysis of 3T3 lysis using Phospho-Fyn (Y530) antibody. Antibody was diluted at 1:2000 -
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using Fyn (Phospho-Tyr530) Antibody. The picture on the right is blocked with the phospho peptide. -
Western blot analysis of lysates from 293 cells treated with H2O2 100uM 15', using Fyn (Phospho-Tyr530) Antibody. The lane on the right is blocked with the phospho peptide.
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