G6PC2 Rabbit Polyclonal Antibody

This gene encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate| the terminal step in gluconeogenic and glycogenolytic pathways| allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity| but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described| but their biological validity has not been determined.

The G6PC2 Rabbit Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of G6PC2 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human G6PC2 protein. The antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The G6PC2 Rabbit Polyclonal Antibody is a valuable tool for researchers studying the role of G6PC2 in glucose homeostasis and diabetes. G6PC2 is a glucose-6-phosphatase catalytic subunit that plays a critical role in regulating glucose metabolism in the liver and pancreas. Dysregulation of G6PC2 has been implicated in the development of type 2 diabetes and other metabolic disorders.

This antibody is supplied as a purified IgG fraction, which has been affinity-purified using a protein A column. The antibody is provided in a liquid format and can be stored at -20°C for long-term storage. The G6PC2 Rabbit Polyclonal Antibody is a reliable and high-quality reagent that can be used for a wide range of applications in basic and clinical research.