GABA A Receptor alpha4 Polyclonal Antibody

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.

The GABA A Receptor alpha4 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of GABA A receptor alpha4 subunit in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target protein.

The GABA A receptor alpha4 subunit plays a crucial role in the modulation of inhibitory neurotransmission in the central nervous system. It is involved in the regulation of neuronal excitability and synaptic transmission, making it an essential component in maintaining the balance of neuronal activity.

This polyclonal antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of GABA A receptor alpha4 subunit in both native and recombinant protein samples.

With its superior performance characteristics, this antibody is an invaluable tool for researchers and scientists studying the function and regulation of GABA A receptor alpha4 subunit. Its application in neuroscience research, drug discovery, and therapeutic development is highly promising.

The GABA A Receptor alpha4 Polyclonal Antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and consistent results. It is available in various sizes to accommodate different experimental needs. Each batch of this antibody undergoes rigorous quality control procedures to ensure batch-to-batch consistency and reproducibility.

In summary, the GABA A Receptor alpha4 Polyclonal Antibody is a highly specific, reliable, and versatile tool for the detection and analysis of GABA A receptor alpha4 subunit. Its exceptional performance characteristics make it an indispensable asset for researchers in the field of neuroscience and related disciplines.