GALR2 Polyclonal Antibody

Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simul

The GALR2 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of the GALR2 protein. This antibody has been extensively validated and exhibits exceptional sensitivity and specificity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The GALR2 Polyclonal Antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. It has been rigorously tested to ensure minimal cross-reactivity with other proteins, guaranteeing accurate and reliable results.

With its superior performance, this antibody enables researchers to investigate the expression and localization of GALR2 in various tissues and cell types. It provides valuable insights into the role of GALR2 in physiological and pathological processes, such as neurotransmission, neurodevelopment, and neurodegenerative diseases.

The GALR2 Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into existing experimental protocols. It is provided in a liquid formulation, ensuring stability and ease of handling.

Choose the GALR2 Polyclonal Antibody for your research needs and unlock the potential of GALR2 protein analysis. With its exceptional performance and reliability, this antibody is an indispensable tool for scientists and researchers in the field of neuroscience and beyond.