PMP22; GAS3; Peripheral myelin protein 22; PMP-22; Growth arrest-specific protein 3; GAS-3
Applications:
WB;IHC;IF;ELISA
Recommended Dilutions:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen:
The antiserum was produced against synthesized peptide derived from human PMP22. AA range:111-160
Storage:
Rabbit
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
22kD
GeneID（Human）:
5376
Human Swiss-Prot No:
Q01453
Cellular localization:
Cell membrane ; Multi-pass membrane protein .
Background:
This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Western Blot analysis of MDA-MB-435 cells using GAS3 Polyclonal Antibody diluted at 1:1000
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PMP22 Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from MDA-MB-435 cells, using PMP22 Antibody. The lane on the right is blocked with the synthesized peptide.