Girdin(Phospho Ser1417) Polyclonal Antibody

This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

The Girdin(Phospho Ser1417) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Girdin protein phosphorylated at Ser1417. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

Girdin, also known as Gα-interacting vesicle-associated protein (GIV), plays a crucial role in various cellular processes, including cell migration, adhesion, and invasion. Phosphorylation of Girdin at Ser1417 has been implicated in the regulation of these processes, making it an important target for research in the field of cell biology and cancer biology.

The Girdin(Phospho Ser1417) Polyclonal Antibody has been rigorously validated for its specificity and sensitivity through various experimental approaches, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated Girdin and other related proteins, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation, ready for immediate use in various applications, including but not limited to Western blotting, immunohistochemistry, and flow cytometry. It is compatible with a wide range of sample types, including cell lysates, tissue extracts, and cultured cells.

With its exceptional performance and reliability, the Girdin(Phospho Ser1417) Polyclonal Antibody is an indispensable tool for researchers studying Girdin signaling pathways and its role in cellular processes. Its high specificity and sensitivity make it an ideal choice for both basic research and clinical applications.