GIT2(Phospho-Tyr392) Rabbit Polyclonal Antibody

This gene encodes a member of the GIT protein family| which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes| focal adhesions| and the cell periphery| and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover| and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms| but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences| with respect to ARF GAP activity and to G

The GIT2(Phospho-Tyr392) Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of GIT2 protein phosphorylated at tyrosine 392 residue. This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring excellent performance and reliability in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The GIT2 protein plays a crucial role in regulating cellular processes such as cell migration, adhesion, and cytoskeletal organization. Phosphorylation of the tyrosine 392 residue is known to modulate the activity and function of GIT2, making it an important target for studying cellular signaling pathways and understanding the mechanisms underlying various diseases.

The GIT2(Phospho-Tyr392) Rabbit Polyclonal Antibody exhibits exceptional specificity towards the phosphorylated form of GIT2, enabling accurate and precise detection of this modified protein. It has been extensively validated in various cell lines and tissues, demonstrating its robustness and reliability in detecting endogenous levels of phosphorylated GIT2.

This antibody is supplied as a liquid formulation, allowing for easy handling and convenient storage. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps. The GIT2(Phospho-Tyr392) Rabbit Polyclonal Antibody is compatible with a wide range of experimental conditions and can be used in both qualitative and quantitative analyses.

In summary, the GIT2(Phospho-Tyr392) Rabbit Polyclonal Antibody is a valuable tool for researchers studying cellular signaling pathways and investigating the role of GIT2 in various biological processes. Its high specificity, sensitivity, and reliability make it an ideal choice for accurate detection and quantification of phosphorylated GIT2 protein.