GIT2(Phospho-Tyr592) Rabbit Polyclonal Antibody

This gene encodes a member of the GIT protein family| which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes| focal adhesions| and the cell periphery| and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover| and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms| but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences| with respect to ARF GAP activity and to G

The GIT2(Phospho-Tyr592) Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of GIT2 protein phosphorylated at tyrosine 592 residue. This antibody has been meticulously developed using advanced immunization techniques and rigorously validated to ensure optimal performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence.

The GIT2 protein plays a crucial role in regulating cellular processes such as cell migration, adhesion, and cytoskeletal organization. Phosphorylation of tyrosine 592 residue is known to modulate the activity and function of GIT2, making it an important target for studying signal transduction pathways and cellular signaling events.

Our GIT2(Phospho-Tyr592) Rabbit Polyclonal Antibody exhibits exceptional specificity, displaying minimal cross-reactivity with non-phosphorylated GIT2 or other related proteins. This ensures accurate and reliable results, enabling researchers to confidently investigate the phosphorylation status of GIT2 in their experimental systems.

With its high sensitivity, this antibody allows for the detection of low abundance phosphorylated GIT2 protein, even in complex biological samples. Its robust performance and reproducibility make it an ideal choice for both qualitative and quantitative analysis of GIT2 phosphorylation.

Furthermore, this GIT2(Phospho-Tyr592) Rabbit Polyclonal Antibody has been extensively validated in various cell lines and tissues, demonstrating consistent and specific staining patterns. Its compatibility with multiple experimental techniques and its versatility in different sample types make it a valuable tool for researchers in the fields of cell biology, molecular biology, and signal transduction.

In summary, the GIT2(Phospho-Tyr592) Rabbit Polyclonal Antibody offers exceptional specificity, sensitivity, and reliability for the detection and quantification of phosphorylated GIT2 protein. Its robust performance and versatility make it an indispensable tool for researchers aiming to unravel the intricate mechanisms underlying cellular signaling pathways.