GLIS3 Rabbit Polyclonal Antibody

This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells| the thyroid| eye| liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined.

The GLIS3 Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of GLIS3 protein expression in various biological samples. This antibody has been meticulously developed and validated to ensure exceptional performance and accuracy in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting applications.

The GLIS3 Rabbit Polyclonal Antibody exhibits a high affinity and specificity towards GLIS3, a transcription factor that plays a crucial role in the regulation of various cellular processes, including embryonic development, cell differentiation, and glucose homeostasis. This antibody recognizes endogenous levels of GLIS3 protein, making it an ideal choice for studying its expression patterns and functional implications in both normal and disease states.

With its superior sensitivity and minimal background noise, this antibody enables precise and reliable detection of GLIS3 protein in a wide range of sample types, including human, mouse, and rat tissues. Its exceptional performance in IHC allows for detailed visualization and localization of GLIS3 within specific cellular compartments, facilitating comprehensive analysis of its subcellular distribution and potential interactions with other proteins.

Furthermore, the GLIS3 Rabbit Polyclonal Antibody demonstrates excellent performance in IF, enabling researchers to investigate the dynamic localization and co-localization of GLIS3 with other cellular markers. This antibody also exhibits robust performance in western blotting, allowing for the accurate quantification of GLIS3 protein levels in various cell lysates and tissue extracts.

In summary, the GLIS3 Rabbit Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of GLIS3 protein expression. Its exceptional performance in IHC, IF, and western blotting applications makes it an invaluable asset for researchers studying GLIS3's role in cellular processes and its potential implications in various diseases.