GNAS2 Rabbit Polyclonal Antibody

This locus has a highly complex imprinted expression pattern. It gives rise to maternally| paternally| and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons| and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus| and the antisense transcript| are paternally expressed noncoding RNAs| and may regulate imprinting in this region. In addition| one of the transcripts contains a second overlapping ORF| which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed| which results in different forms of the stimulatory G-protein alpha subunit| a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene result in pseudohypoparathyroidism type 1a| pseudohypoparathyroidism type 1b| Albright hereditary osteodystrophy| pseudopseudohypoparathyroidism| McCune-Albright syndrome| progressive osseus heteroplasia| polyostotic fibrous dysplasia of bone| and some pituitary tumors.

The GNAS2 Rabbit Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and analysis of GNAS2 protein expression in various biological samples. This antibody has been meticulously developed using advanced techniques to ensure exceptional performance and reliability.

The GNAS2 Rabbit Polyclonal Antibody exhibits a high affinity towards the GNAS2 protein, enabling accurate and precise detection even at low expression levels. It has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring batch-to-batch consistency and reproducibility. It has been rigorously tested to ensure minimal cross-reactivity with other proteins, ensuring specific and reliable results.

The GNAS2 Rabbit Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming and complex preparation steps.

With its exceptional sensitivity, specificity, and ease of use, the GNAS2 Rabbit Polyclonal Antibody is an indispensable tool for researchers and scientists studying GNAS2 protein expression and its role in various biological processes.