GPX2 Rabbit Polyclonal Antibody

The protein encoded by this gene belongs to the glutathione peroxidase family| members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione| and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates| which vary in cellular location and substrate specificity. This isozyme is predominantly expressed in the gastrointestinal tract (also in liver in human)| is localized in the cytoplasm| and whose preferred substrate is hydrogen peroxide. Overexpression of this gene is associated with increased differentiation and proliferation in colorectal cancer. This isozyme is also a selenoprotein| containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon| which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure| designated the Sec insertion sequence (SECIS) element| that is necessary for the recognition of UGA as a Sec codon| rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.

The INT8 Rabbit Polyclonal Antibody is a highly specific and reliable tool for various research applications. This antibody has been meticulously developed and validated to ensure exceptional performance and accuracy in detecting INT8 protein expression.

With its polyclonal nature, this antibody exhibits a broad reactivity, making it suitable for a wide range of species, including human, mouse, and rat. Its versatility allows for seamless integration into diverse experimental setups, enabling researchers to explore the role of INT8 in different biological systems.

The INT8 Rabbit Polyclonal Antibody boasts exceptional sensitivity, enabling the detection of even low levels of INT8 protein expression. This attribute is particularly advantageous when studying samples with limited protein availability or when investigating subtle changes in INT8 expression levels.

Furthermore, this antibody demonstrates outstanding specificity, ensuring minimal cross-reactivity with other proteins. This specificity is crucial for obtaining reliable and accurate results, as it eliminates the risk of false positives or misleading data.

The INT8 Rabbit Polyclonal Antibody is supplied in a convenient and user-friendly format, allowing for easy handling and storage. Its long shelf life guarantees consistent performance over an extended period, ensuring reliable results throughout your research endeavors.

In summary, the INT8 Rabbit Polyclonal Antibody is a highly specific, sensitive, and versatile tool that facilitates the investigation of INT8 protein expression in various research applications. Its exceptional performance, reliability, and user-friendly format make it an invaluable asset for researchers aiming to unravel the intricacies of INT8's biological functions.