BT Lab
SKU(재고 관리 코드):BT-AP15784
GRIP-1(Phospho Ser736) Polyclonal Antibody
GRIP-1(Phospho Ser736) Polyclonal Antibody
The protein encoded by this gene functions as a transcriptional coactivator for nuclear hormone receptors, including steroid, thyroid, retinoid, and vitamin D receptors. The encoded protein acts as an intermediary factor for the ligand-dependent activity of these nuclear receptors, which regulate their target genes upon binding of cognate response elements. This gene has been found to be involved in translocations that result in fusions with other genes in various cancers, including the lysine acetyltransferase 6A (KAT6A) gene in acute myeloid leukemia, the ETS variant 6 (ETV6) gene in acute lymphoblastic leukemia, and the hes related family bHLH transcription factor with YRPW motif 1 (HEY1) gene in mesenchymal chondrosarcoma. Alternative splicing results in multiple transcript variants.
The GRIP-1(Phospho Ser736) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of GRIP-1 protein phosphorylated at Ser736. This antibody is produced using advanced polyclonal antibody production techniques, ensuring high affinity and specificity towards the target protein.
GRIP-1, also known as glutamate receptor interacting protein 1, plays a crucial role in the regulation of glutamate receptor trafficking and synaptic plasticity. Phosphorylation of GRIP-1 at Ser736 has been implicated in various cellular processes, including synaptic transmission and neuronal development.
The GRIP-1(Phospho Ser736) Polyclonal Antibody has been rigorously validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, enabling accurate and reliable detection of phosphorylated GRIP-1 protein in various biological samples.
This antibody is supplied as a liquid formulation, allowing for easy handling and storage. It is provided in a convenient size, ensuring cost-effectiveness and minimizing wastage. The GRIP-1(Phospho Ser736) Polyclonal Antibody is suitable for use in both research and diagnostic applications, aiding in the understanding of GRIP-1 function and its role in various physiological and pathological conditions.
In summary, the GRIP-1(Phospho Ser736) Polyclonal Antibody is a valuable tool for researchers and clinicians alike, offering high specificity, sensitivity, and versatility in the detection and quantification of phosphorylated GRIP-1 protein. Its reliable performance and ease of use make it an essential component in studies related to glutamate receptor trafficking, synaptic plasticity, and neuronal development.