HES3 Polyclonal Antibody

Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG).,The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins.,Transcriptional repressor of genes that require a bHLH protein for their transcription.,Contains 1 basic helix-loop-helix (bHLH) domain.,Contains 1 Orange domain.,subunit:Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family.,

The HES3 Polyclonal Antibody is a highly specific and sensitive antibody that has been designed to detect and quantify the expression of HES3 protein in various biological samples. This antibody has been extensively validated for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The HES3 protein is a transcriptional repressor that plays a critical role in the regulation of cell fate determination and differentiation. It is expressed in a variety of tissues, including the brain, heart, and skeletal muscle, and has been implicated in the development of several diseases, including cancer.

The HES3 Polyclonal Antibody has been produced using high-quality materials and state-of-the-art techniques to ensure maximum specificity and sensitivity. It has been rigorously tested to ensure that it meets the highest standards of quality and performance.

This antibody is supplied in a convenient format that is easy to use and can be stored at -20°C for long-term storage. It is suitable for use in a variety of research applications and is an essential tool for researchers studying the role of HES3 in development and disease.