Histone H2A (Acetyl Lys96) Rabbit Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A| H2B| H3| and H4) form an octamer| around which approximately 146 bp of DNA is wrapped in repeating units| called nucleosomes.

The linker histone| H1| interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.

The Histone H2A (Acetyl Lys96) Rabbit Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of Histone H2A acetylated at Lysine 96. This antibody has been meticulously developed using advanced immunization techniques, resulting in a high affinity and specificity towards the target antigen.

Histone H2A is a crucial component of the nucleosome, playing a pivotal role in chromatin structure and gene regulation. Acetylation of Lysine 96 on Histone H2A has been implicated in various biological processes, including transcriptional activation and DNA repair. Therefore, the ability to accurately detect and quantify Histone H2A acetylated at Lysine 96 is of utmost importance in understanding the intricate mechanisms underlying these processes.

The Histone H2A (Acetyl Lys96) Rabbit Polyclonal Antibody exhibits exceptional sensitivity and selectivity, enabling precise detection and quantification of Histone H2A acetylated at Lysine 96 in various sample types, including cell lysates and tissue sections. Its robust performance ensures reliable and reproducible results, making it an indispensable tool for researchers in the fields of epigenetics, chromatin biology, and gene regulation.

Furthermore, this antibody has been rigorously validated through multiple experimental approaches, including Western blotting, immunohistochemistry, and immunofluorescence. Its outstanding performance in these applications further attests to its reliability and versatility.

In summary, the Histone H2A (Acetyl Lys96) Rabbit Polyclonal Antibody is a highly specific and sensitive tool that enables accurate detection and quantification of Histone H2A acetylated at Lysine 96. Its exceptional performance, reliability, and versatility make it an invaluable asset for researchers seeking to unravel the intricate mechanisms of chromatin biology and gene regulation.