Histone H3 (Mono Methyl Arg17) Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. HIST1H3A (histone cluster 1 H3 family member a) is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. HIST1H3A is found in the large histone gene cluster on chromosome 6p22-p21.3.

The Histone H3 (Mono Methyl Arg17) Polyclonal Antibody is a highly specific and sensitive tool for the detection and analysis of histone H3 protein modifications. This antibody is designed to specifically recognize and bind to the mono methylated form of arginine 17 on histone H3, allowing for precise and accurate identification of this specific modification.

With its polyclonal nature, this antibody offers enhanced sensitivity and versatility, making it suitable for a wide range of applications including Western blotting, immunohistochemistry, and chromatin immunoprecipitation. Its high affinity and specificity ensure reliable and reproducible results, enabling researchers to confidently investigate the role of histone H3 mono methylation in various biological processes and disease states.

Manufactured using state-of-the-art techniques and quality control measures, this antibody guarantees consistent performance and batch-to-batch reproducibility. It is produced in a host species that minimizes non-specific binding, further enhancing its specificity and reducing background noise.

The Histone H3 (Mono Methyl Arg17) Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into existing laboratory protocols. It is provided in a liquid formulation, eliminating the need for reconstitution and ensuring optimal stability and shelf life.

Choose the Histone H3 (Mono Methyl Arg17) Polyclonal Antibody for reliable and accurate detection of histone H3 mono methylation, and unlock new insights into the complex world of epigenetics.