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ELK Biotechnology
SKU(재고 관리 코드):ES7968
Hrs (phospho Tyr334) Rabbit Polyclonal Antibody
Hrs (phospho Tyr334) Rabbit Polyclonal Antibody
Hrs (phospho Tyr334) Rabbit Polyclonal Antibody
Overview
| Product name: | Hrs (phospho Tyr334) rabbit pAb |
| Alternative Names: | HGS; HRS; Hepatocyte growth factor-regulated tyrosine kinase substrate; Hrs; Protein pp110 |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human HRS around the phosphorylation site of Tyr334. AA range:301-350 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 86kD |
| GeneID(Human): | 9146 |
| Human Swiss-Prot No: | O14964 |
| Cellular localization: | Cytoplasm . Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Endosome, multivesicular body membrane ; Peripheral membrane protein . Colocalizes with UBQLN1 in ubiquitin-rich cytoplasmic aggregates that are not endocytic compartments. . |
| Background: | The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. [provided by RefSeq, Dec 2010], |
| Species Reactivity: | Human;Mouse;Rat |
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Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using HRS (Phospho-Tyr334) Antibody -
Immunofluorescence analysis of HeLa cells treated with Forskolin 40nM 15', using HRS (Phospho-Tyr334) Antibody. The picture on the right is blocked with the phospho peptide. -
Immunohistochemistry analysis of paraffin-embedded human brain, using HRS (Phospho-Tyr334) Antibody. The picture on the right is blocked with the phospho peptide. -
Western blot analysis of lysates from HepG2 cells treated with PMA 125ng/ml 30', using HRS (Phospho-Tyr334) Antibody. The lane on the right is blocked with the phospho peptide.
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