HtrA2(Phospho Ser212) Polyclonal Antibody

This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

The HtrA2(Phospho Ser212) Polyclonal Antibody is a highly specific and sensitive tool for the detection and quantification of HtrA2 protein phosphorylated at Serine 212. This antibody has been rigorously validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

HtrA2, also known as Omi, is a serine protease that plays a crucial role in cellular homeostasis and apoptosis. Phosphorylation of HtrA2 at Serine 212 has been implicated in the regulation of its enzymatic activity and subcellular localization. Therefore, the ability to specifically detect and quantify phosphorylated HtrA2 is of great importance in understanding its functional role in various biological processes.

The HtrA2(Phospho Ser212) Polyclonal Antibody has been developed using high-quality immunogens and state-of-the-art techniques to ensure exceptional specificity and sensitivity. It has been extensively tested and validated using a variety of cell lysates and tissue samples, demonstrating its reliability and accuracy in detecting phosphorylated HtrA2.

This antibody exhibits minimal cross-reactivity with non-phosphorylated HtrA2 and other related proteins, ensuring reliable and specific results. It is supplied as a ready-to-use solution, allowing for convenient and efficient use in various experimental settings.

In summary, the HtrA2(Phospho Ser212) Polyclonal Antibody is a valuable tool for researchers studying the role of HtrA2 phosphorylation in cellular processes. Its high specificity, sensitivity, and reliability make it an ideal choice for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.