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Elabscience
SKU(재고 관리 코드):E-EL-H0915
Human P-GP(Permeability Glycoprotein) ELISA Kit
Human P-GP(Permeability Glycoprotein) ELISA Kit
The Human P-GP (Permeability Glycoprotein) ELISA Kit is a highly sensitive and specific assay designed to measure the levels of P-GP in human samples. P-GP is a membrane-bound protein that plays a crucial role in the transport of drugs and other molecules across cell membranes. It is expressed in a variety of tissues, including the liver, kidney, intestine, and brain, and is involved in the absorption, distribution, and elimination of many drugs.
The ELISA kit is based on the sandwich enzyme-linked immunosorbent assay (ELISA) technique, which uses two antibodies that bind to different epitopes on the P-GP molecule. The first antibody is coated onto the wells of a microtiter plate, and the sample is added to the wells. The P-GP in the sample binds to the first antibody, and the second antibody, which is conjugated to an enzyme, is added. The enzyme catalyzes a colorimetric reaction that produces a signal that is proportional to the amount of P-GP in the sample.
The Human P-GP ELISA Kit is a valuable tool for researchers studying the role of P-GP in drug transport and metabolism. It is also useful for clinicians who need to monitor P-GP levels in patients receiving chemotherapy or other drugs that are substrates for P-GP. The kit is easy to use, with a simple protocol that can be completed in less than 4 hours. It has a wide dynamic range and high sensitivity, with a detection limit of 0.1 ng/mL. The kit is supplied with all the necessary reagents and controls, and can be used with a variety of sample types, including serum, plasma, and tissue homogenates.
The ELISA kit is based on the sandwich enzyme-linked immunosorbent assay (ELISA) technique, which uses two antibodies that bind to different epitopes on the P-GP molecule. The first antibody is coated onto the wells of a microtiter plate, and the sample is added to the wells. The P-GP in the sample binds to the first antibody, and the second antibody, which is conjugated to an enzyme, is added. The enzyme catalyzes a colorimetric reaction that produces a signal that is proportional to the amount of P-GP in the sample.
The Human P-GP ELISA Kit is a valuable tool for researchers studying the role of P-GP in drug transport and metabolism. It is also useful for clinicians who need to monitor P-GP levels in patients receiving chemotherapy or other drugs that are substrates for P-GP. The kit is easy to use, with a simple protocol that can be completed in less than 4 hours. It has a wide dynamic range and high sensitivity, with a detection limit of 0.1 ng/mL. The kit is supplied with all the necessary reagents and controls, and can be used with a variety of sample types, including serum, plasma, and tissue homogenates.
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