I-TAC Rabbit Polyclonal Antibody

disease:Expressed in a variety of skin disorders| including allergic contact dermatitis| lichen planus and mycosis fungoides.|Chemotactic for interleukin-activated T-cells but not unstimulated T-cells| neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.|induction:By interferon gamma and interferon beta.

Induction by IFN-gamma is enhanced by TNF-alpha in monocytes| dermal fibroblasts and endothelial cells| and by IL-1 in astrocytes.|mass spectrometry: PubMed:10233762|online information:CXCL11 entry|Belongs to the intercrine alpha (chemokine CxC) family.|tissue specificity:High levels in peripheral blood leukocytes| pancreas and liver astrocytes. Moderate levels in thymus| spleen and lung. Low levels in placenta| prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders.|

The I-TAC Rabbit Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of I-TAC protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the I-TAC protein.

The I-TAC Rabbit Polyclonal Antibody exhibits exceptional affinity and selectivity towards the target protein, ensuring accurate and reliable results. It has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and enzyme-linked immunosorbent assays (ELISA).

With its superior sensitivity, this antibody enables the detection of even low levels of I-TAC protein, making it an invaluable tool for researchers studying chemokine signaling pathways and investigating the role of I-TAC in various physiological and pathological processes.

The I-TAC Rabbit Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a ready-to-use format, eliminating the need for time-consuming reconstitution or dilution steps.

This antibody is manufactured under strict quality control standards to ensure consistent performance and reproducibility. Each batch is rigorously tested to meet the highest standards of specificity, sensitivity, and lot-to-lot consistency.

Choose the I-TAC Rabbit Polyclonal Antibody for its exceptional performance, reliability, and ease of use. It is an indispensable tool for researchers in the field of immunology, molecular biology, and biomedical sciences.