IFN- gammaR alpha(Phospho Tyr457) Polyclonal Antibody

This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition| defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease| also known as familial disseminated atypical mycobacterial infection.

The IFN-gammaR alpha(Phospho Tyr457) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of the phosphorylated form of the IFN-gamma receptor alpha subunit at tyrosine residue 457. This antibody is produced using advanced polyclonal antibody technology, ensuring high affinity and specificity towards the target protein.

The IFN-gamma receptor alpha subunit plays a crucial role in the signaling pathway of interferon-gamma, a key cytokine involved in immune responses and inflammation. Phosphorylation of tyrosine residue 457 is known to regulate the activation and downstream signaling of the IFN-gamma receptor alpha subunit.

This polyclonal antibody is rigorously validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of the phosphorylated IFN-gamma receptor alpha subunit.

With its superior quality and performance, the IFN-gammaR alpha(Phospho Tyr457) Polyclonal Antibody is an indispensable tool for researchers and scientists studying the intricate mechanisms of interferon-gamma signaling and its implications in various biological processes.